Vegan diet could be an anti-ageing and weight-loss hack, study of identical twins suggests

These changes were not seen in the twins whose diet included meat, eggs and dairy products.

Those who ate a vegan diet also lost 2kg more on average than those who did not, probably because of differences in the calorie content of meals provided during the initial four weeks of the study.
According to experts, the weight loss could have contributed to the observed differences in biological age between the groups.
The sibling who ate only plant-based meals for eight weeks showed signs of a decrease in biological ageing. Photo: Shutterstock

Some experts suggested that, long-term, a vegan diet may result in nutritional deficiencies and may not suit all ages, while others said the differences observed in the study could have been down to weight loss.

By the end of the study, the researchers observed decreases in biological age estimations based on levels of DNA methylation – a type of chemical modification of DNA that is used to estimate biological age.

Biological ageing refers to the decline in functioning of tissues and cells in the body, as opposed to chronological age (the number of years a person has lived).

Previous research has reported that increased DNA methylation levels are associated with ageing.

However, Varun Dwaraka, of epigenetic testing company TruDiagnostic, and Christopher Gardner of Stanford University in California, said it was unclear to what extent the differences between the pairs could be attributed to the differences in diet.

The vegan group was asked to eat twice the number of portions of vegetables, and more fruit and more legumes, nuts and seeds than the omnivorous group. Photo: Shutterstock

Tom Sanders, professor emeritus of nutrition and dietetics at King’s College London, in the UK, who was not involved in the study, said the research found some difference in terms of ageing for vegans.

He noted that it did not consider the fact that vitamin and mineral deficiencies often take years to appear, and that some research suggests a vegan diet may not be good for older people’s health.

Dr Duane Mellor, dietitian and spokesman for the British Dietetic Association, said that although the study compared a vegan diet to an omnivorous diet, these diets were not entirely matched in terms of calories.

He explained: “It is possible that a reduction in energy intake could potentially have altered how the participants’ DNA was changed.”

The findings are published in the journal BMC Medicine.

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